Karen, works with Penny at Zangen. Penny claims that she stole her yogurt. Bernadette tells Penny that she is going to offer the Sales Team leadership position to Karen that Penny turned down, using it as a ploy to make Penny take the position. At the first Sales Team meeting Karen objects to having to memorize all the new drug's specifications so quickly. Penny snaps and asks if she wants a yogurt. In "The Conference Valuation", Karen is first seen very tired at a midnight session of Penny's sales team. Later she is seen at the pharmaceutical convention in the Zangen booth. She also tells Bernadette that another company offered her a job.