Jane Frances Kaczmarek is an American actress. She is best known for playing the character of Lois on the television series "Malcolm in the Middle" (2000–06). Kaczmarek is a three-time Golden Globe and seven-time Emmy Award nominee. She was born in Milwaukee, Wisconsin, the daughter of Evelyn (née Gregorska), a teacher, and Edward Kaczmarek, a US Department of Defense worker. Of Polish ancestry, she grew up in Greendale, where she was raised a Roman Catholic. She majored in theater at the University of Wisconsin–Madison and later attended graduate school at the Yale School of Drama. In 1998, Kaczmarek was cast as David and Jennifer's mother in the movie "Pleasantville". She has had several Broadway hits, including "Lost in Yonkers" and "Raised in Captivity", where she won an L.A. Drama Critics Circle Award. Her first television role was that of Margie Spoletto on "For Lovers Only" (1982). One of her first notable appearances was in the famous 1984 movie "Falling in Love", starring Meryl Streep and Robert De Niro, playing the role of Ann Raftis, De Niro's character's wife. She also played a role in "The Heavenly Kid" in 1985 as Emily. In "The Big Bang Theory" she played the psychiatrist in "The Sales Call Sublimation".