Flora is Amy Farrah Fowler's great-aunt. When she was having her 93rd birthday party, Sheldon, who had promised Amy that he would go, changes his mind and doesn't go so he can play the online Star Wars game with the other guys all weekend. Amy is very disappointed since she wanted to show her relatives that she has a real boyfriend.
Amy also has an aunt in Modesto, California and another one in Bakersfield.