watch 01:48 The Loop (TV) Do you like this video? Amy's grandmother is the deceased grandmother of Amy. She has been shown and mentioned a few times. She was either the mother of Mr. Fowler or Mrs. Fowler. She is shown on a picture in "The Emotion Detection Automation". Retrieved from "https://bigbangtheory.fandom.com/wiki/Amy%27s_Grandmother?oldid=268994" Categories: Characters Deceased Characters Amy Female Characters Mentioned-only Characters Season 10 Grandmothers Community content is available under CC-BY-SA unless otherwise noted.