She Blinded Me with Science

She Blinded me with Science was a hit song in the 80's by Thomas Dolby. It served as the theme tune for the opening of the unaired pilot, and is occasionally heard as Howard's phone ringtone.

Although a success in the United States, peaking at No. 5 in the Billboard Hot 100 and 2 weeks at No. 1 in Canada's RPM Magazine, the song barely managed to score among the Top 50 in Dolby's native United Kingdom, peaking at No. 49 in the UK Singles Chart.