The Isolation Permutation

"The Isolation Permutation" is the eighth episode of the fifth season of The Big Bang Theory. This episode first aired on November 3, 2011.

Summary
Amy is hurt when Bernadette and Penny go bridesmaid dress shopping without her, so she turns to a reluctant Sheldon for comfort.

Extended Plot
Amy, Penny and Bernadette are excitedly discussing dresses for Bernadette's wedding. Sheldon gets fed up with the quality of conversation, unsuccessfully trying to be discreet in his blaming Penny for it, and attempts to discuss the validity of a Swiss discovery concerning faster-than-light particles at CERN, after which the three women leave for Penny's apartment. The next day, Amy is in the Caltech cafeteria after being given a grant to purchase a strain of Mad Cow Disease, making everyone uncomfortable. However, Howard absentmindedly complains at constantly being texted non-stop by Bernadette with pictures of the dresses they want to buy. This makes Amy realize they are doing it without her, and she leaves, looking visibly upset.

Later, Leonard is playing Horse racing with Xbox Kinect, but Sheldon becomes concerned when Amy doesn't respond to any of his attempts to contact her, and Leonard offers to drive him there to find out what's going on. When they arrive, she is playing "Everybody Hurts" on her harp, while crying, and Sheldon, unwilling to proceed, attempts to persuade Leonard to take him home. Leonard, however, sees an opportunity and immediately knocks on Amy's door using Sheldon's knock, and leaves, stranding Sheldon at Amy's apartment. He says that he doesn't have to put up with this because he is single.Amy initially desires to be left alone, but she invites him in, and explains that Penny and Bernadette's snubbing her has left her feeling depressed. After asking him to keep an open mind, she explains her desire for physical contact, and makes a list of proposals involving them getting intimate, while Sheldon makes a series of counter-proposals (French kissing) that involve less intimacy (patting her and neck massage), but will still be soothing to her. They eventually agree to just cuddle, and she snuggles up to him on her couch.

The next morning, however, Sheldon storms into the cafeteria and confronts Howard and Leonard, explaining that his night of building a Lego Death Starhad been ruined by his having to spoon with Amy, and demanding that they get Penny and Bernadette to apologize to Amy (even though Leonard is not Penny's boyfriend)

That evening, after Howard and Leonard explain what happened, Penny and Bernadette are dismayed, and explain they had gone without Amy because she was over-enthusiastic and would've been a hindrance to their dress shopping. They never-the-less feel guilty, and visit Amy at her laboratory to apologize. However, their efforts to do so are merely brushed off by Amy, who describes herself as a "tumor" in an otherwise functional brain.



That night, Sheldon gets a call from Amy, who has gotten drunk in a liquor store parking lot, and he and Leonard rush over to help her. She once again attempts to persuade Sheldon to have sex with her at a nearby motel, and embarrasses him by calling him "cuddles." He instead insists that he and Leonard take her home, and Leonard helps her up finding Amy's "second base". The next day, Penny and Bernadette return to Amy's laboratory, and Bernadette, in an effort to apologize to her once and for all, asks her to be her Maid of Honor. Amy is immediately excited and forgives them at once.



The episode ends with Amy filming a dress shopping trip with Penny and Bernadette as part of the pre-wedding events. She is as over-enthusiastic as they'd feared. She agrees that Bernadette is beautiful in a wedding dress, but not "Penny beautiful" which annoys them. Penny is taking a long time so Amy barges into Penny's dressing room while she's in her underwear taking a second look as she leaves.

Trivia

 * Sheldon originally designated the night he spent with Amy for solving the Spacetime Geometry in Higher Spin Gravity and building a Lego Death Star.
 * On Amazon.com, the Lego Death Star seen in this episode costs $898.98.
 * Raj understands fashion and dresses.
 * Leonard refers to himself as "single" in this episode, confirming he and Priya have broken up after the events of the previous episode.
 * Leonard is too tall to be a jockey and is afraid of horses.
 * Amy had a semester away in Norway and her so-called friends locked her in the sauna with a horny otter.
 * Amy had a cousin who died the day before her wedding due to gas inhalation. She was supposed to be the Maid of Honor and the dresses are still unused.
 * In "The Infestation Hypothesis", Amy claims to know only two songs she can play on her harp, "The Girl From Ipanema" and the theme song to "Diff'rent Strokes." She has now added "Everybody Hurts" to her repertoire.
 * For someone with an eidetic memory and an IQ of 187, Sheldon did not think to try to reach Amy by telephoning her, an idea Leonard gave him after he complained that all his other communication methods have failed. This suggests a theory that people who are smarter, have less common sense.
 * Sheldon is someone who detests touching and other forms of physical contact. However, during his counter-offers with Amy at her apartment, he did suggest to stroke her head, give her a neck massage, and later on agreed to cuddle with her. He treats Amy different than any other of his friends and colleagues.
 * Sheldon has always emphasized how Amy is not his girlfriend, but when a drunk Amy called him "Cuddles" at the parking lot, earning a frown from Leonard, Sheldon simply said "Yes, Cuddles, we cuddled. Grow up, Leonard," indicating that he does not care what his friends might say regarding his relationship with Amy.
 * For the first time ever, Leonard is seen imitating Sheldon's knock.
 * Amy's claims that Leonard found "second base" which seems to be the side of her breast.
 * Sheldon shows his affection for Amy for he agrees to cuddle with her despite his fear of human contact.
 * Penny is seen wearing the bridesmaid dress style she wore at the wedding, while Bernadette is not wearing the wedding dress she wore at her wedding. Amy is also wearing a different dress.

Critics
"This was a solid attempt to make Amy a more sympathetic character. She doesn't really seem to learn much by the end of the episode but at least her vulnerability added an extra layer for us to see...Of course the conclusion of the story demonstrated why Amy is a trying friend. She is rude and pushy and made dress shopping more about her than the bride...So often the instincts of the writers are good (Amy needs to be humanised) but their execution isn't right (she remains basically unchanged)." - The TV Critic's Review

Quotes
Amy: Wait for moi!

Sheldon: ''Wha.. you're leaving?''

Amy: ''Sheldon, sometimes you forget, I'm a lady. And with that comes an estogren-fuelled need to page through thick, glossy magazines that make me hate my body.''

Sheldon: ''Stand back! While I turn this conversation into a conver-sensation.''

Leonard: How long will it take for Mad Cow disease to kill me?

Amy: Four, five years.

Leonard: No, that's not gonna do it.

Leonard: I would have been a great jockey had I not been too tall...

Sheldon: Leonard, in your own simple way, you may be the wisest of us all.

Amy:'' I was hoping you wouldn't notice. Irene was always a slave to a good bargain, and sadly as it turned out, space heaters. ''

Sheldon: ''She sounds weepy. I don't like weepy.''

(Leonard imitates Sheldon's Knock)

Leonard: (knocks x 3) Amy, (knocks x 3) Amy, (knocks x 3) Amy. (Walks away).

Sheldon: Where are you going?!

Leonard: I'm single, I don't need this crap.

Sheldon: ''Would you like to talk about it? And keep in mind that 'no' is a perfectly viable answer.''

Amy: ''Oh, look. It’s Sheldon and little Leonard. Hi, little Leonard.''

Leonard: Hi, Amy.

Amy: Hey, Cuddles.

Leonard: Cuddles?

Sheldon: ''Yes, Cuddles. We cuddled. Grow up, Leonard.''

Leonard: Amy, what are you doing here?

Amy: Well, I came here to get a bottle of wine like Penny taught me to do when you’re sad.

Leonard: Yeah, but why didn’t you go back to your apartment?

Amy: ''Didn’t you go to high school, Leonard? Parking lots are where all the cool kids hang out. Not that the rat bastards ever invited me.''

Leonard: Maybe we should get you home.

Amy: ''Oh, hang on, hang on, hang on. Sheldon, what would it take for you to go into that liquor store, buy a bottle of hooch, take me across the street to that motel, and have your way with me?''

Leonard: Yeah, Sheldon, what would it take?

Sheldon: I’m begging both of you, please, let’s go.

Leonard: ''Okay. Come on. Upsy-daisy.''

Amy: ''Whee! Ooh, finally someone found second base.''

Amy: Sheldon, I’m going to ask you something, and I’d like you to keep an open mind.

Sheldon: Always.

Amy: At this moment, I find myself craving human intimacy and physical contact.

Sheldon: ''Oh, boy. You know ours is a relationship of the mind.''

Amy: ''Proposal. One wild night of torrid lovemaking that soothes my soul and inflames my loins.''

Sheldon: ''Counterproposal. I will gently stroke your head and repeat, aw, who’s a good Amy.''

Amy: ''How about this? French kissing, seven minutes in heaven culminating in second base.''

Sheldon: Neck massage, then you get me that beverage.

Amy: ''We cuddle. Final offer.''

Sheldon: ''Very well. Oh, boy.'' (They cuddle, awkwardly.)

Amy: I’m just saying, second base is right there.

Video
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