The Vacation Solution

"The Vacation Solution" is the sixteenth episode of the fifth season of ''The Big Bang Theory. ''This episode first aired on February 9, 2012.

Summary
When Sheldon has to take a vacation, he ends up testing his relationship with Amy when he goes to work in her lab. Howard is being forced to sign a pre-nuptial agreement by Bernadette's father.

Extended Plot
Sheldon is forced to take a vacation by the university president. After a failed attempt at sneaking into work, Sheldon takes a cue from Richard Feynman and dabbles in biology at Amy's lab. She has him cleaning laboratory glassware and counting growth cultures in Petri dishes and failing at both tasks. Sheldon insists that with his intelligence he can do more. When Amy lets him try to dissect a brain, he faints after he cuts his thumb. Later he does go back to apologize after drinking virgin piña coladas in The Cheesecake Factory bar while Howard and Penny admonish his actions.

Meanwhile, Bernadette's father wants Howard to sign a pre-nuptial agreement which he unfortunately hears about through the nerd grapevine. He's reluctant to sign, and tells her that he'll go talk to her father himself. When Bernadette explains her father still carries his police revolver, he decides to put off the discussion until after he's up on the International Space Station.

At the Cheesecake Factory bar, Penny sets both Howard and Sheldon straight. She tells Howard how lucky he is to have Bernadette and he should sign anything put in front of him. According to Penny he will never find anyone else as good as Bernadette because all the women had a meeting and decided that. Sheldon gets scolded for fainting at the sight of a little blood. He claims that it is not a little cut and then faints again after showing it to Penny.

Critics
"In terms of story I didn't think much was done to flesh out Sheldon's arrogance. We know that he thinks he is a genius but he should have enough logic to know some basic facts. Of course he wouldn't be able to dissect a brain without first studying what each tiny part of it was called or practising with easier tasks first...This was a flat episode which continued themes we've seen many times before." - The TV Critic's Review

Quotes
Sheldon: They tried to make Richard Feynman take a vacation, but he chose instead to expand his mind and learn something new. He went to work in his friend's biology lab. (aside to Howard) Richard Feynman was a famous American physicist—part of the Manhattan Project.

Howard: Everyone in the world of science knows who Richard Feynman was.

Sheldon: Now you do, too.

Howard: Isn't that just Feynman's idea?

Sheldon: Ten seconds ago you never heard of him- now you're an expert.

Raj: Mr. Roper is dead? You can't just spring that on a guy!

Sheldon: (Carrying a tray of beakers) Here you go! This is now the only lab with glassware washed by a man with two doctorates and a restraining order signed by Carl Sagan.

Amy: (Inspects a beaker) Soap spots! Wash 'em again.

Sheldon: You're being ridiculous! Those are perfectly clean.

Amy: Sheldon, this beaker used to contain cerebral spinal fluid from an elephant that died of syphilis. If it is, in fact, perfectly clean, drink from it!

Sheldon: (Picks up the tray of beakers again) Biologists are mean!

Penny: Ha ha, you cut your thumb and fainted!

Sheldon: What do we start with? Slicing some genes? Clone a sheep? Perhaps grow a human ear on a mouse's back? Haha! (laughs)

Amy: I'm excited to work with my boyfriend, it's gonna be romantic.

Sheldon: Way to kill the mood.

Amy: Are we nervous, Dr. Cooper?

Sheldon: No. What you see is a man trembling with confidence... Does the locus coeruleus usually bleed that much?

Amy: No, but your thumb does.

Sheldon: Oh dear! (faints)

Amy: Yeah, YOU'RE a biologist.

Sheldon: I have plenty of experience in biology. I bought a Tamagotchi in 1998... And.... it's still alive.

Sheldon: Excuse me, but you have Doctor Cooper in your lab! Are you gonna make him do the dishes? That's like asking The Incredible Hulk to open a pickle jar.

Raj: No 'Hi, Raj!', no 'How are you, Raj?', just straight to 'Where's the other white guy?'?

Trivia

 * Joshua Malina, who plays President Siebert, last appeared during Season 4's "The Benefactor Factor". This is his second appearance on the show.
 * In "The Peanut Reaction", Howard gets Leonard an autographed copy of  as Sheldon partly complains about gift giving on hearing this, so Sheldon's assertion of Howard's complete ignorance regarding in "The Vacation Solution" is inconsistent. Yet, the matter can be attributed to "Sheldon’s patented blend of condescension" (as Howard mused in "The Flaming Spittoon Acquisition"), for Sheldon ignores Howard's claim that every scientist in the world knows of Feynman.
 * In "The Luminous Fish Effect", based on the work of ese scientists, Sheldon inserts  from into a, successfully creating a . He also reveals his idea of what DNA would look like in a silicon-based life form (see silicon-based lifeforms in Star Trek). In "The Bad Fish Paradigm", Sheldon refers to the  of an   in . In "The Griffin Equivalency", Sheldon references his childhood studies in . In "The Alien Parasite Hypothesis", he participates in a . Hence, it isn't the field of  in general that he lacks skill in, but it is the physical practice of biology in a lab that seems to give him difficulty.
 * Sheldon visited Amy's lab previously in "The Alien Parasite Hypothesis".
 * Sheldon says, "Maybe, that's because I'm not being challenged. It's the same reason failed math." Einstein actually obtained exceptional grades in mathematics.
 * Bernadette's father still has his gun, as a fashion statement, even though he is retired as a police officer. She also says that he is racist,, , and hates , gardeners, , the , , , the , and.
 * The Wolowitzs have adjoining plots in the, next to the grave of (who is actually buried above ground in a vault).
 * Sheldon won't go to, as it was the place of the finale of Lost, has active es, and is a former . He also won't go to because he went there on a family vacation and a  took his hotdog (see "The Ornithophobia Diffusion" for other bird incidents).
 * Penny sees sex as a valuable tool for manipulation.
 * This is the first time we hear Sheldon laugh properly, which is over a game of Physics . The only other time he has laughed like that is when Leonard made a multiplication error. Leonard says that isn't funny as it was published.
 * Amy is one of the few characters in the show who has shown little toleration for Sheldon's narcissism and condescension, seeing how she makes him apologize for his rude behavior.
 * The, which Amy is working on removing from a brain in her lab, is found in the , which is located in the , and is involved responses to  and . Amy compares the width of the locus coeruleus to that of a single human hair, the diameter of which ranges from 17 to 181 µm (millionths of a meter).
 * Howard explains that he has an Aunt Ida who lives in Florida.
 * After all of Sheldon's troubles in Amy's lab, he tells himself next year he will go to in, Florida, which has exhibits honoring various branches of the sciences.